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Childhood Diseases Dataset – Pediatric Conditions & Disorders Database

Childhood Diseases Dataset

The Childhood Diseases Dataset is a structured medical database containing a comprehensive list of diseases and health conditions affecting infants, children, and adolescents.

Children are susceptible to a wide range of illnesses, from common infections to genetic and developmental disorders. This dataset provides organised information to support pediatric research, healthcare analytics, and application development.

Each record includes detailed clinical information such as disease descriptions, affected body systems, common symptoms, severity levels, and typical treatment approaches.

The dataset has been cleaned and structured for easy integration into spreadsheets, databases, and analytical tools.

It is ideal for pediatricians, healthcare developers, researchers, educators, and data scientists working with child health data.

Dataset Contents

The dataset includes fields such as:

Disease / Condition Name
Description
Affected System
Common Symptoms
Severity Level
Disease Category
Age Group (Infant, Child, Adolescent)
Treatment / Management

Example Conditions Included

Chickenpox
Measles
Mumps
Whooping Cough (Pertussis)
Scarlet Fever
Bronchiolitis
Hand, Foot, and Mouth Disease
Croup
Pediatric Asthma
Ear Infections (Otitis Media)

...and many more childhood diseases.

File Size 37.3 KB

Records 110

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17 columns 25 rows shown

	ID	Disease Name	Category	Prevalence	Inheritance Pattern	Affected Gene(s)	Chromosome Location	Key Symptoms	Typical Age of Onset	Diagnosis Methods	Available Treatments	Orphan Drug Designation	ICD-10 Code	OMIM Number	Affected System	Disease Severity	Life Expectancy Impact
1	1	Neonatal Respiratory Distress Syndrome (RDS)	Neonatal/Respiratory	~1% of all births; up to 60% of <28-week preterms	Multifactorial (prematurity)	SFTPB, SFTPC, ABCA3 (rare hereditary forms)	2p11.2, 8p21.3, 16p13.3	Tachypnea, grunting, nasal flaring, retractions, cyanosis within hours of birth	Newborn (preterm)	Clinical, CXR (diffuse ground-glass, air bronchograms), blood gases, surfactant studies	Antenatal corticosteroids, exogenous surfactant, CPAP, mechanical ventilation, oxygen	No	P22.0	267450	Respiratory	Severe	Improves with treatment
2	2	Bronchopulmonary Dysplasia (BPD)	Neonatal/Respiratory	~10,000-15,000 cases/yr (US)	Acquired (preterm sequela)	N/A	N/A	Persistent oxygen need at 36 weeks PMA, tachypnea, retractions, poor weight gain, recurrent infections	Preterm infants	Clinical (oxygen need at 36 wk PMA), CXR, lung function	Oxygen, diuretics, bronchodilators, inhaled steroids, nutrition, RSV prophylaxis	No	P27.1	N/A	Respiratory	Severe	Variable
3	3	Necrotizing Enterocolitis (NEC)	Neonatal/GI	1-3 per 1000 live births; ~7% of VLBW infants	Acquired (multifactorial)	N/A	N/A	Feeding intolerance, abdominal distension, bloody stools, lethargy, apnea, shock	Newborn (mostly preterm)	Abdominal X-ray (pneumatosis intestinalis, portal venous gas), CBC, blood gases, blood culture	Bowel rest, NG decompression, broad-spectrum antibiotics, TPN, surgery for perforation	No	P77.9	N/A	GI	Severe	Reduced (mortality 20-30%)
4	4	Intraventricular Hemorrhage (IVH) of Prematurity	Neonatal/Neurology	~25% of VLBW infants	Acquired (prematurity)	N/A	N/A	Often asymptomatic; may have sudden deterioration, bulging fontanelle, seizures, anemia, apnea	Newborn (first week of life)	Cranial ultrasound, MRI	Supportive care, blood pressure stabilization, treatment of hydrocephalus (VP shunt)	No	P52.3	N/A	CNS	Severe	Variable (depends on grade)
5	5	Hypoxic-Ischemic Encephalopathy (HIE)	Neonatal/Neurology	1-3 per 1000 term births	Acquired (perinatal asphyxia)	N/A	N/A	Depressed consciousness, hypotonia, abnormal reflexes, seizures, multi-organ dysfunction	Newborn	Apgar scores, cord blood gas, EEG, MRI, aEEG	Therapeutic hypothermia (within 6 hr), supportive care, anticonvulsants	No	P91.6	N/A	CNS	Severe	Reduced (CP risk, mortality)
6	6	Neonatal Jaundice (Physiologic & Pathologic)	Neonatal/Hematology	~60% term, 80% preterm	Multifactorial	UGT1A1 (Gilbert; Crigler-Najjar variants)	2q37.1	Yellow skin and sclera, lethargy, poor feeding; kernicterus if severe	Newborn (24-72 hr typical)	Total/direct bilirubin, Coombs, blood type, CBC, G6PD	Phototherapy, hydration, exchange transfusion, IVIG (isoimmune)	No	P59.9	N/A	Hepatobiliary	Variable	Normal with treatment
7	7	Neonatal Sepsis (Early & Late Onset)	Neonatal/Infectious	1-8 per 1000 live births	Acquired	N/A	N/A	Temperature instability, lethargy, poor feeding, respiratory distress, apnea, jaundice, shock	Newborn	Blood culture, CBC with differential, CRP, procalcitonin, LP, urine culture	Empiric broad-spectrum antibiotics (ampicillin + gentamicin), supportive care, antifungals if needed	No	P36.9	N/A	Multisystem	Severe	Reduced (mortality 10-20%)
8	8	Transient Tachypnea of the Newborn (TTN)	Neonatal/Respiratory	~5.7 per 1000 term births	Acquired	N/A	N/A	Tachypnea, mild grunting, nasal flaring within hours of birth, resolves in 24-72 hr	Newborn	CXR (perihilar streaking, fluid in fissures), clinical, exclusion of other causes	Supportive: oxygen, CPAP if needed, observation	No	P22.1	N/A	Respiratory	Mild	Normal
9	9	Meconium Aspiration Syndrome (MAS)	Neonatal/Respiratory	~5% of MSAF deliveries	Acquired	N/A	N/A	Meconium-stained fluid, respiratory distress at birth, hypoxia, persistent pulmonary hypertension	Newborn (term/post-term)	CXR (patchy infiltrates, hyperinflation), clinical, blood gases	Suction if obstructed airway, surfactant, mechanical ventilation, iNO, ECMO if severe	No	P24.01	N/A	Respiratory	Severe	Variable
10	10	Persistent Pulmonary Hypertension of Newborn (PPHN)	Neonatal/Cardiopulmonary	~2 per 1000 live births	Acquired	N/A	N/A	Severe cyanosis, labile oxygenation, respiratory distress, differential pulse oximetry	Newborn	Echocardiogram (right-to-left shunt, elevated PA pressure), pre/post-ductal SpO2	Oxygen, mechanical ventilation, iNO, sildenafil, milrinone, ECMO	No	P29.30	N/A	Cardiopulmonary	Severe	Reduced if untreated
11	11	Retinopathy of Prematurity (ROP)	Neonatal/Ophthalmology	~16,000 affected/yr (US)	Acquired (prematurity, oxygen exposure)	N/A	N/A	Abnormal retinal vascularization, leukocoria, strabismus, retinal detachment in severe cases	Preterm infants (32-34 wk PMA screening)	Indirect ophthalmoscopy, retinal imaging	Laser photocoagulation, anti-VEGF (bevacizumab, ranibizumab), vitrectomy	No	H35.10	N/A	Eye	Variable	Normal vision possible with treatment
12	12	Neonatal Hypoglycemia	Neonatal/Metabolic	~10-15% of all newborns	Acquired (multifactorial)	N/A	N/A	Jitteriness, lethargy, poor feeding, hypotonia, apnea, seizures, hypothermia	Newborn (first 24-72 hr)	POC glucose (<47 mg/dL), serum glucose, critical sample if persistent	Early feeding, IV dextrose (D10W), glucagon, treat underlying cause	No	P70.4	N/A	Metabolic	Variable	Normal with treatment
13	13	Measles (Rubeola)	Infectious/Viral	~9 million cases/yr globally	Acquired (Measles morbillivirus)	N/A	N/A	High fever, cough, coryza, conjunctivitis, Koplik spots, maculopapular rash starting cephalad	Childhood (1-4 yr unvaccinated)	Measles IgM serology, RT-PCR, clinical	Supportive care, vitamin A, MMR vaccine for prevention; ribavirin in severe cases	No	B05.9	N/A	Multisystem	Severe	Mostly normal; complications can be fatal
14	14	Mumps	Infectious/Viral	Sporadic in vaccinated populations	Acquired (Mumps virus, Paramyxoviridae)	N/A	N/A	Parotitis (uni/bilateral), fever, malaise, orchitis (postpubertal), meningitis, oophoritis	School-age children	RT-PCR, IgM serology, clinical	Supportive care, NSAIDs, MMR vaccine for prevention	No	B26.9	N/A	Salivary glands/multisystem	Moderate	Normal
15	15	Rubella (German Measles)	Infectious/Viral	Eliminated in many vaccinated countries	Acquired (Rubella virus, Togaviridae)	N/A	N/A	Mild fever, postauricular lymphadenopathy, fine pink rash; congenital rubella syndrome if pregnant	Children (unvaccinated)	Rubella IgM serology, RT-PCR	Supportive; MMR vaccine for prevention	No	B06.9	N/A	Multisystem	Mild	Normal (devastating in fetus)
16	16	Varicella (Chickenpox)	Infectious/Viral	~4 million cases/yr (US pre-vaccine)	Acquired (Varicella-zoster virus)	N/A	N/A	Pruritic vesicular rash in crops, fever, malaise; reactivation as zoster later	Childhood (under 10)	Clinical; PCR/DFA from vesicles	Supportive; acyclovir in severe cases or immunocompromised; varicella vaccine for prevention	No	B01.9	N/A	Skin/multisystem	Mild	Normal
17	17	Respiratory Syncytial Virus (RSV) Bronchiolitis	Infectious/Viral	~57,000 hospitalizations/yr (US <5)	Acquired (RSV)	N/A	N/A	Rhinorrhea, cough, wheeze, tachypnea, retractions, apnea (young infants), hypoxia	Infants <2 yr	Clinical; nasopharyngeal RSV antigen/PCR	Supportive (oxygen, hydration, suction); palivizumab/nirsevimab for prevention; RSV vaccines (mother, infant)	No	J21.0	N/A	Respiratory	Variable	Normal in most
18	18	Hand-Foot-and-Mouth Disease	Infectious/Viral	Common worldwide outbreaks	Acquired (Coxsackievirus A16, EV-71)	N/A	N/A	Low fever, oral ulcers, vesicular rash on palms, soles, buttocks; herpangina	Infants and young children	Clinical; viral PCR if needed	Supportive: hydration, analgesics; isolation	No	B08.4	N/A	Skin/oral	Mild	Normal
19	19	Roseola Infantum (Sixth Disease)	Infectious/Viral	~95% of children by age 2	Acquired (HHV-6, HHV-7)	N/A	N/A	High fever for 3-5 days, then maculopapular rash on trunk; febrile seizures possible	6 months-2 years	Clinical; serology rarely needed	Supportive: antipyretics, hydration	No	B08.20	N/A	Skin/multisystem	Mild	Normal
20	20	Erythema Infectiosum (Fifth Disease)	Infectious/Viral	Common in school-age children	Acquired (Parvovirus B19)	N/A	N/A	Mild prodrome, slapped-cheek rash, lacy reticular rash on extremities; aplastic crisis in SCD; hydrops in fetus	School-age (5-15 yr)	Clinical; B19 IgM serology, PCR	Supportive; transfusions for aplastic crisis; IVIG in immunocompromised	No	B08.3	N/A	Skin/hematologic	Mild	Normal
21	21	Croup (Laryngotracheobronchitis)	Infectious/Viral	~3% of children/yr	Acquired (Parainfluenza 1, 2, 3, RSV)	N/A	N/A	Barking cough, inspiratory stridor, hoarseness, low-grade fever, worse at night	6 months-3 yr	Clinical (Westley score); X-ray neck shows steeple sign	Single-dose oral dexamethasone, nebulized epinephrine, humidified oxygen	No	J05.0	N/A	Upper airway	Mild	Normal
22	22	Pertussis (Whooping Cough)	Infectious/Bacterial	Resurgent (~150,000 cases/yr globally)	Acquired (Bordetella pertussis)	N/A	N/A	Catarrhal then paroxysmal coughing fits with inspiratory whoop, post-tussive emesis, apnea (infants)	Infants and unvaccinated children	PCR from nasopharyngeal swab, culture, serology	Macrolide (azithromycin), supportive; DTaP/Tdap vaccination	No	A37.90	N/A	Respiratory	Severe in infants	Normal with treatment
23	23	Diphtheria	Infectious/Bacterial	Rare in vaccinated populations	Acquired (Corynebacterium diphtheriae)	N/A	N/A	Sore throat, low fever, pseudomembrane on tonsils/pharynx, bull neck, myocarditis, neuropathy	Unvaccinated children	Throat culture, toxin assay	Diphtheria antitoxin, erythromycin/penicillin, DTaP vaccine for prevention	No	A36.9	N/A	Respiratory/cardiac	Severe	Reduced (mortality 5-10%)
24	24	Tetanus (Pediatric/Neonatal)	Infectious/Bacterial	~25,000 neonatal deaths/yr globally	Acquired (Clostridium tetani toxin)	N/A	N/A	Trismus, risus sardonicus, opisthotonus, muscle spasms, autonomic dysfunction	Any age (unvaccinated)	Clinical; wound history	Tetanus immunoglobulin (TIG), metronidazole, wound debridement, supportive ICU care; DTaP vaccine	No	A35	N/A	CNS/musculoskeletal	Severe	Reduced (mortality high)
25	25	Poliomyelitis	Infectious/Viral	Wild polio near eradication; vaccine-derived cases reported	Acquired (Poliovirus)	N/A	N/A	Asymptomatic, abortive, non-paralytic meningitis, or acute flaccid paralysis with asymmetric weakness	Children (mostly <5)	Stool/throat culture, RT-PCR, CSF analysis	Supportive only; IPV/OPV vaccine for prevention	No	A80.9	N/A	Motor neurons	Severe	Variable (post-polio syndrome)

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Childhood Diseases Dataset – Pediatric Conditions & Disorders Database