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Zoonotic Diseases

A reference to diseases transmitted between animals and humans, covering causative agents, exposure routes, symptoms, diagnosis, treatment and health impacts.

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A reference to diseases transmitted between animals and humans, covering causative agents, exposure routes, symptoms, diagnosis, treatment and health impacts.
110records
17columns
CSV + Excel

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5 sample rows · 110 records in the full fileScroll across
Sample rows from Zoonotic Diseases. Field types are labelled in each column heading.
#TextIDTextDisease NameTextCategoryTextPrevalenceTextInheritance PatternTextAffected Gene(s)LocationChromosome LocationTextKey SymptomsTextTypical Age of OnsetTextDiagnosis MethodsTextAvailable TreatmentsTextOrphan Drug DesignationTextICD-10 CodeNumberOMIM NumberTextAffected SystemTextDisease SeverityTextLife Expectancy Impact
011Rabies (Classical, Dog-mediated)Viral Zoonosis~59,000 human deaths/yr globally (mostly Asia/Africa)Acquired (Lyssavirus - bite/scratch from infected mammal, mainly dogs)N/AN/AProdrome (fever, paresthesia at bite), encephalitic (hydrophobia, aerophobia, agitation) or paralytic form, near-100% fatal once symptomaticAll agesClinical + exposure history; antemortem RT-PCR (saliva, skin biopsy nape), Negri bodies postmortem, RFFIT serologyUS CDC PEP: wound cleansing; previously unvaccinated patients receive HRIG plus IM vaccine on days 0, 3, 7 and 14 (add day 28 and assess antibody response if immunocompromised). Previously vaccinated patients receive vaccine on days 0 and 3, without HRIG. PEP prevents disease before symptoms; established rabies requires specialist supportive care.NoA82.9N/ACentral nervous systemSevereReduced (>99% fatal once symptomatic)
022Rabies (Sylvatic - Bat/Wildlife)Viral ZoonosisMost US cases bat-related; raccoon, fox, skunk in wildlifeAcquired (bat lyssavirus, raccoon variant - bite, scratch, mucosal contact)N/AN/ASame as classical rabies; bat exposures may go unrecognizedAll agesExposure history (bat in room), RT-PCR, IFA on brain biopsyPEP for any unprovoked wildlife bite, all bat exposures, vaccine + RIGNoA82.0N/ACentral nervous systemSevereReduced
033Australian Bat Lyssavirus (ABLV)Viral ZoonosisRare; Australia (flying foxes, microbats)Acquired (ABLV - bat bite/scratch)N/AN/ARabies-like encephalitis, uniformly fatal; only 3 reported human casesAll agesRT-PCR, IFA, serologyStandard rabies PEP (vaccine + HRIG), supportive ICUNoA82.0N/ACentral nervous systemSevereReduced (fatal)
044European Bat Lyssavirus (EBLV-1/2)Viral ZoonosisRare; Europe (Serotine and Daubenton's bats)Acquired (EBLV - bat bite)N/AN/ARabies-like encephalitis, fatalAll agesRT-PCR, IFARabies PEP (cross-protective vaccine), supportiveNoA82.0N/ACentral nervous systemSevereReduced
055Nipah Virus EncephalitisViral ZoonosisOutbreaks in Bangladesh, India, Malaysia (~40-75% case fatality)Acquired (Pteropus fruit bats - contaminated date palm sap, intermediate pigs, person-to-person)N/AN/AFever, headache, encephalitis, seizures, coma, ARDS; high mortalityAll agesRT-PCR (CSF, throat), IgM/IgG ELISA, virus isolation BSL-4Supportive ICU; ribavirin and monoclonal antibody (m102.4) experimental; isolation precautionsNoB33.8N/ACentral nervous system/RespiratorySevereReduced
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