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Viral Diseases
An overview of viral diseases and viruses, covering virus families, transmission, symptoms, incubation periods, diagnosis, treatment, prevention and geographic distribution.
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An overview of viral diseases and viruses, covering virus families, transmission, symptoms, incubation periods, diagnosis, treatment, prevention and geographic distribution.
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84records
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| # | TextNo. | TextDisease / Virus Name | TextType | TextVirus Family | TextTransmission | TextAffected Systems | TextSymptoms | TextIncubation Period | TextDiagnosis | TextTreatment | TextPrevention | TextGeographic Distribution | TextMortality Rate | TextNotable Information |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | 1 | Adenoviral keratoconjunctivitis | Disease | Adenoviridae | Direct contact; fomites; contaminated ophthalmic instruments; respiratory droplets | Eyes | Severe conjunctival inflammation; keratitis; photophobia; tearing; foreign body sensation; subepithelial corneal infiltrates; lid oedema; preauricular lymphadenopathy | 5-12 days | Clinical examination; viral culture; PCR of conjunctival swab; immunochromatography (AdenoPlus rapid test) | Supportive care (cold compresses, artificial tears); no specific antiviral; topical corticosteroids for subepithelial infiltrates (controversial); cidofovir (investigational) | Strict hand hygiene; disinfection of ophthalmic equipment; avoid sharing towels/eye cosmetics; isolation of infected individuals | Worldwide; epidemic outbreaks in hospitals, military barracks, swimming pools | Extremely rare (essentially 0%) | Caused mainly by adenovirus serotypes 8, 19, 37; highly contagious; epidemic keratoconjunctivitis (EKC) is the most severe form; corneal opacities can persist for months to years |
| 02 | 2 | Amur virus | Virus | Hantaviridae (Bunyavirales) | Inhalation of aerosolised rodent excreta (urine, droppings, saliva) from Korean field mouse (Apodemus peninsulae) | Kidneys; vascular system | Haemorrhagic fever with renal syndrome (HFRS): fever; headache; myalgia; abdominal pain; haemorrhagic manifestations; renal failure; hypotension; thrombocytopaenia | 2-4 weeks | Serology (IgM/IgG ELISA); RT-PCR; immunofluorescence assay | Supportive care; fluid management; dialysis if needed; ribavirin (investigational, may reduce mortality if given early) | Rodent control; avoid contact with rodent excreta; proper ventilation when cleaning rodent-infested areas | Far East Russia; northeastern China; Korea | ~5-15% (HFRS) | Closely related to Hantaan virus; named after Amur River region; carried by Apodemus peninsulae; causes moderate to severe HFRS |
| 03 | 3 | Andes virus | Virus | Hantaviridae (Bunyavirales) | Inhalation of aerosolised rodent excreta from long-tailed colilargo (Oligoryzomys longicaudatus); person-to-person transmission documented | Lungs; vascular system | Hantavirus pulmonary syndrome (HPS): prodromal fever, myalgia, headache followed by rapid-onset non-cardiogenic pulmonary oedema; respiratory failure; shock; thrombocytopaenia | 1-5 weeks (average 2 weeks) | Serology (IgM ELISA); RT-PCR; immunohistochemistry | Intensive supportive care; mechanical ventilation; ECMO in severe cases; no approved antiviral | Rodent control; avoid contact with rodent excreta; infection control for person-to-person risk; proper PPE | South America (Argentina, Chile, Brazil, Uruguay, Paraguay, Bolivia) | ~25-40% (HPS) | Only hantavirus with confirmed person-to-person transmission; first identified in 1995 in Argentina; can cause both HPS and HFRS-like illness |
| 04 | 4 | Astrovirus | Virus | Astroviridae | Faecal-oral route; contaminated food and water; person-to-person contact | Gastrointestinal tract | Watery diarrhoea; nausea; vomiting; abdominal cramps; low-grade fever; malaise; typically milder than rotavirus | 1-4 days | Electron microscopy (star-shaped morphology); ELISA; RT-PCR; immunochromatography | Supportive care; oral or IV rehydration; no specific antiviral | Hand hygiene; safe food/water handling; environmental disinfection | Worldwide | Very low (<0.1%); deaths rare, mainly in immunocompromised or malnourished children | Named for star-like appearance under electron microscopy; common cause of viral gastroenteritis in children (after rotavirus and norovirus); 8 human serotypes (HAstV 1-8); serotype 1 most prevalent |
| 05 | 5 | Bas-Congo virus | Virus | Rhabdoviridae | Suspected person-to-person (exact mechanism unknown); possibly via body fluids; insect vectors suspected | Vascular system; multi-organ | Acute haemorrhagic fever; fever; headache; vomiting; bloody diarrhoea; epistaxis; gingival bleeding; conjunctival injection | Unknown (estimated 2-10 days based on case cluster) | RT-PCR; next-generation sequencing; serology (neutralisation assay) | Supportive care; no specific antiviral available | Standard infection control precautions; contact and droplet precautions; further research needed | Democratic Republic of Congo (Bas-Congo province) | ~2 of 3 known cases fatal (~67%) | Cases occurred in 2009; virus identified via retrospective sequencing and published in 2012; novel rhabdovirus; only 3 cases reported (2 fatal); first rhabdovirus associated with acute haemorrhagic fever in humans; natural reservoir unknown |
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