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Tropical Diseases

An overview of diseases associated with tropical regions, covering causative agents, transmission or exposure, symptoms, diagnosis, treatment and health impacts.

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An overview of diseases associated with tropical regions, covering causative agents, transmission or exposure, symptoms, diagnosis, treatment and health impacts.

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110records
17columns
CSV + Excel + JSONformats
5 sample rows · 110 records in the full fileScroll across
Sample rows from Tropical Diseases. Field types are labelled in each column heading.
#TextIDTextDisease NameTextCategoryTextPrevalenceTextInheritance PatternTextAffected Gene(s)LocationChromosome LocationTextKey SymptomsTextTypical Age of OnsetTextDiagnosis MethodsTextAvailable TreatmentsTextOrphan Drug DesignationTextICD-10 CodeNumberOMIM NumberTextAffected SystemTextDisease SeverityTextLife Expectancy Impact
011Dengue FeverMosquito-borne Viral~390 million infections/yr globallyAcquired (Aedes aegypti, A. albopictus)N/AN/AHigh fever, severe headache, retro-orbital pain, myalgia, arthralgia, rash, hemorrhagic manifestations, plasma leak (DHF/DSS)Any ageNS1 antigen, IgM/IgG ELISA, RT-PCR, tourniquet test, CBC (thrombocytopenia)Supportive (fluids, paracetamol; avoid NSAIDs/aspirin), CYD-TDV (Dengvaxia) and TAK-003 (Qdenga) vaccinesNoA90N/AMultisystemVariableVariable (severe forms reduced)
022Yellow FeverMosquito-borne Viral~200,000 cases, 30,000 deaths/yrAcquired (Aedes/Haemagogus mosquitoes)N/AN/AFever, jaundice, hemorrhage, hepatorenal failure, Faget sign (bradycardia with fever), black vomitAny ageRT-PCR, IgM ELISA, viral culture, LFTsSupportive ICU care; live-attenuated 17D vaccine (highly effective, lifelong immunity)NoA95.9N/AHepatic/MultisystemSevereReduced (mortality 20-50%)
033Zika Virus DiseaseMosquito-borne ViralEndemic in Americas, Asia, AfricaAcquired (Aedes mosquitoes; sexual, vertical)N/AN/AMild fever, maculopapular rash, conjunctivitis, arthralgia; congenital microcephaly, GBSAny age (severe in fetuses)RT-PCR (blood/urine), IgM serology, plaque reduction neutralizationSupportive; avoid pregnancy in endemic areas; vector controlNoA92.5N/AMultisystem/CNSVariableNormal in adults; severe congenital effects
044ChikungunyaMosquito-borne ViralOutbreaks in tropics globallyAcquired (Aedes mosquitoes)N/AN/ASudden high fever, severe symmetric polyarthralgia (often persistent), rash, myalgia, headacheAny ageRT-PCR (acute), IgM/IgG ELISA, PRNTSupportive (NSAIDs, paracetamol); IXCHIQ live-attenuated vaccine (FDA-approved 2023)NoA92.0N/AMusculoskeletalVariableNormal (chronic arthralgia common)
055Japanese EncephalitisMosquito-borne Viral~68,000 cases/yr (Asia)Acquired (Culex tritaeniorhynchus)N/AN/AFever, headache, vomiting, altered mental status, seizures, parkinsonism, flaccid paralysisChildren/young adultsIgM in CSF/serum, RT-PCR, MRI (thalamic/basal ganglia lesions)Supportive ICU care; inactivated and live attenuated vaccines (SA 14-14-2, IXIARO)NoA83.0N/ACNSSevereReduced (mortality 20-30%)
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