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Pregnancy Related Diseases

A reference to conditions affecting pregnancy and maternal or fetal health, covering risk factors, symptoms, timing, diagnosis, treatment options and complications.

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About this dataset

A reference to conditions affecting pregnancy and maternal or fetal health, covering risk factors, symptoms, timing, diagnosis, treatment options and complications.

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133records
17columns
CSV + Excel + JSONformats
5 sample rows · 133 records in the full fileScroll across
Sample rows from Pregnancy Related Diseases. Field types are labelled in each column heading.
#TextIDTextDisease NameTextCategoryTextPrevalenceTextInheritance PatternTextAffected Gene(s)LocationChromosome LocationTextKey SymptomsTextTypical Age of OnsetTextDiagnosis MethodsTextAvailable TreatmentsTextOrphan Drug DesignationTextICD-10 CodeNumberOMIM NumberTextAffected System(s)TextDisease SeverityTextLife Expectancy Impact
011Chronic Hypertension in PregnancyHypertensive Disorders1-5% of pregnanciesAcquired / MultifactorialN/AN/ABP >=140/90 before 20 weeks gestation or pre-pregnancy; often asymptomatic; headache, visual changes if severePre-pregnancy or <20 weeksPre-pregnancy BP records; BP measurement <20 weeks; 24-hour ambulatory BPLabetalol, nifedipine XL, methyldopa; low-dose aspirin 81 mg from 12 weeks for preeclampsia preventionNoO10.919N/ACardiovascular / MaternalModerateMinimal with control
022Gestational HypertensionHypertensive Disorders6-17% of nulliparous pregnanciesAcquired / MultifactorialN/AN/ANew-onset BP >=140/90 after 20 weeks without proteinuria or end-organ dysfunctionAfter 20 weeks gestationSerial BP measurements; urine protein; laboratory surveillance for progressionLabetalol, nifedipine; antenatal surveillance; delivery by 37 weeksNoO13.9N/ACardiovascular / MaternalModerateMinimal with treatment
033Preeclampsia without Severe FeaturesHypertensive Disorders3-5% of pregnanciesAcquired / MultifactorialN/AN/ABP >=140/90 plus proteinuria (>=300 mg/24h) after 20 weeks; may have edema, mild headacheAfter 20 weeks gestationBP measurement; urine protein:creatinine ratio; CBC, LFTs, creatinine; uric acidAntihypertensives (labetalol, nifedipine); antenatal surveillance; delivery at 37 weeksNoO14.00N/AMulti-system / Maternal-FetalModerate to SevereReduced without treatment
044Preeclampsia with Severe FeaturesHypertensive Disorders1-2% of pregnanciesAcquired / MultifactorialN/AN/ABP >=160/110; severe headache, visual disturbance, RUQ pain, pulmonary edema, thrombocytopenia, elevated LFTs, oliguriaAfter 20 weeks gestationBP criteria; CBC (platelets <100k); AST/ALT 2x ULN; creatinine >1.1; clinical symptomsIV magnesium sulfate for seizure prophylaxis; IV labetalol/hydralazine/oral nifedipine; delivery at 34 weeksNoO14.10N/AMulti-system / Maternal-FetalSevereReduced without treatment
055HELLP SyndromeHypertensive Disorders0.2-0.8% of pregnancies; 10-20% of severe preeclampsiaAcquired / MultifactorialN/AN/AHemolysis, elevated liver enzymes, low platelets; RUQ pain, nausea, malaise; may lack hypertensionThird trimester or postpartum (up to 7 days)Peripheral smear (schistocytes); LDH >600; AST/ALT >2x ULN; platelets <100k; haptoglobin lowIV magnesium sulfate; BP control; corticosteroids; prompt delivery; platelet transfusion if <20k or bleedingNoO14.20N/AHepatic / Hematologic / MaternalSevereReduced without treatment
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