Sample rows from Occupational Diseases. Field types are labelled in each column heading.
#	TextID	TextDisease Name	TextCategory	TextPrevalence	TextInheritance Pattern	TextAffected Gene(s)	LocationChromosome Location	TextKey Symptoms	TextTypical Age of Onset	TextDiagnosis Methods	TextAvailable Treatments	TextOrphan Drug Designation	TextICD-10 Code	NumberOMIM Number	TextAffected System	TextDisease Severity	TextLife Expectancy Impact
01	1	Silicosis (Chronic)	Pneumoconiosis	~2.3 million workers exposed (US); millions globally	Acquired (crystalline silica dust inhalation - mining, quarrying, sandblasting, stonework)	N/A	N/A	Progressive dyspnea, dry cough, chest tightness, fatigue; nodular fibrosis on CXR (eggshell hilar calcifications), accelerated decline with PMF	10-30 yr after exposure (adults)	Occupational history, CXR/HRCT (ILO classification), PFTs (restrictive), bronchoscopy if needed	No cure; remove exposure, bronchodilators, oxygen, lung transplant for advanced; screen for TB	No	J62.8	N/A	Respiratory	Severe	Reduced (PMF, TB, lung cancer risk)
02	2	Acute Silicosis (Silicoproteinosis)	Pneumoconiosis	Rare; very high silica exposure (sandblasters, drillers)	Acquired (massive crystalline silica inhalation)	N/A	N/A	Rapidly progressive dyspnea over weeks-months, cough, weight loss, hypoxemia, alveolar proteinosis pattern	Months to <5 yr after intense exposure	HRCT (crazy paving), BAL (PAS-positive material), occupational history	Whole-lung lavage, supportive O2, lung transplant; remove from exposure	No	J62.8	N/A	Respiratory	Severe	Reduced (often fatal within years)
03	3	Asbestosis	Pneumoconiosis	~125 million workers exposed historically	Acquired (asbestos fiber inhalation - mining, insulation, shipyards, construction)	N/A	N/A	Insidious dyspnea on exertion, dry cough, bibasilar inspiratory crackles, clubbing, restrictive PFTs	20-40 yr latency (adults)	Occupational history, CXR/HRCT (subpleural reticular fibrosis, pleural plaques), PFTs, BAL ferruginous bodies	Supportive (oxygen, vaccines, smoking cessation), pulmonary rehab; lung transplant rare; surveillance for cancer	No	J61	N/A	Respiratory	Severe	Reduced (mesothelioma/lung cancer risk)
04	4	Coal Workers' Pneumoconiosis (Black Lung)	Pneumoconiosis	~10% of US coal miners with >25 yr underground	Acquired (coal mine dust inhalation)	N/A	N/A	Simple CWP often asymptomatic; complicated (PMF): dyspnea, melanoptysis, cor pulmonale, restrictive/obstructive PFTs	15-20 yr after exposure	Occupational history, CXR (small rounded opacities, ILO classification), HRCT, PFTs	No specific treatment; remove from exposure, smoking cessation, bronchodilators/O2, federal black lung benefits	No	J60	N/A	Respiratory	Variable	Reduced (PMF, TB risk)
05	5	Berylliosis (Chronic Beryllium Disease)	Pneumoconiosis	~1-15% of beryllium-exposed workers (sensitized)	Acquired (beryllium inhalation - aerospace, nuclear, ceramics, electronics)	Host: HLA-DPB1 (Glu69) marked susceptibility	6p21.32	Dyspnea on exertion, dry cough, fatigue, weight loss, granulomatous lung disease (sarcoid-like), skin granulomas	Months to decades after exposure	Beryllium lymphocyte proliferation test (BeLPT), HRCT, transbronchial biopsy (non-caseating granulomas)	Corticosteroids, methotrexate, infliximab; remove from exposure, oxygen	No	J63.2	N/A	Respiratory/Multisystem	Severe	Variable

Occupational Diseases

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