Sample rows from Geriatric Diseases. Field types are labelled in each column heading.
#	TextID	TextDisease Name	TextCategory	TextPrevalence	TextInheritance Pattern	TextAffected Gene(s)	LocationChromosome Location	TextKey Symptoms	TextTypical Age of Onset	TextDiagnosis Methods	TextAvailable Treatments	TextOrphan Drug Designation	TextICD-10 Code	NumberOMIM Number	TextAffected System(s)	TextDisease Severity	TextLife Expectancy Impact
01	1	Frailty Syndrome	Geriatric Syndromes	Approximately 10-15% of community-dwelling adults >65 years; rises to >25% in adults >85 (Fried phenotype; Lancet 2019)	Acquired / Multifactorial	N/A	N/A	Unintentional weight loss, exhaustion, weakness (low grip strength), slow gait speed, low physical activity	65+ years	Fried phenotype criteria, Clinical Frailty Scale, FRAIL scale, comprehensive geriatric assessment	Resistance/aerobic exercise, protein-rich nutrition, vitamin D, medication review, multidisciplinary CGA	No	R54	N/A	Multisystem	Variable	Moderate reduction
02	2	Sarcopenia	Geriatric Syndromes	Approximately 10-11% in community-dwelling adults >60 years (EWGSOP2); up to 27% in adults >=85 (J Clin Med 2024)	Acquired / Multifactorial	N/A	N/A	Progressive loss of muscle mass and strength, low grip strength, slow gait speed, poor physical performance	65+ years	EWGSOP2 criteria: SARC-F screen, grip strength, DXA/BIA for muscle mass, gait speed/SPPB	Progressive resistance training, protein supplementation (1.0-1.2 g/kg/day), vitamin D, treat underlying conditions	No	M62.84	N/A	Musculoskeletal	Variable	Mild reduction
03	3	Recurrent Falls in Older Adults	Geriatric Syndromes	1 in 4 adults aged >=65 falls annually (CDC 2024); fall death rate 78.4 per 100,000 older adults	Acquired / Multifactorial	N/A	N/A	Two or more falls in 12 months, injury, fear of falling, gait and balance impairment	65+ years	CDC STEADI algorithm, Timed Up and Go, 30-second chair stand, 4-stage balance test, medication review	Exercise (tai chi, Otago), vitamin D if deficient, home hazard modification, deprescribing, vision correction	No	R29.6	N/A	Musculoskeletal	Variable	Moderate reduction
04	4	Delirium	Geriatric Syndromes	Approximately 23% pooled prevalence in hospitalized older adults; up to 50% in ICU/post-surgical (Int J Nurs Stud 2024)	Acquired / Multifactorial	N/A	N/A	Acute onset, fluctuating course, inattention, disorganized thinking, altered level of consciousness	65+ years	CAM (Confusion Assessment Method), 3D-CAM, CAM-ICU, DSM-5-TR criteria, identify precipitants	Treat underlying cause, non-pharmacologic (HELP protocol), reorientation, minimize sedatives, low-dose antipsychotics if severe	No	F05	N/A	Neurologic	Severe	Moderate reduction
05	5	Pressure Injury, Unspecified Site and Stage	Geriatric Syndromes	Approximately 11% of US nursing home residents (CDC NCHS); 2.5 million US cases annually	Acquired / Multifactorial	N/A	N/A	Localized skin/tissue damage over bony prominence, erythema, ulceration, exposure of muscle/bone in severe stages	65+ years	NPUAP/EPUAP staging (I-IV, unstageable, deep tissue), Braden Scale risk assessment, clinical exam	Pressure redistribution, repositioning q2h, support surfaces, wound care, nutrition optimization, debridement (WHS 2023)	No	L89.90	N/A	Integumentary	Variable	Mild reduction

Geriatric Diseases

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