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Antibiotics- 1
Dofil -A structured reference of 149 antibiotics grouped by pharmacological class
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Last updated01 September 2026
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A structured reference of 149 antibiotics grouped by pharmacological class, covering generic and brand names, common clinical uses, possible side effects, and mechanism of action. Sourced and fact-checked against current prescribing references.
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| No. | Generic Name | Brand Names | Common Uses | Possible Side Effects | Mechanism of Action | Family | Class |
|---|---|---|---|---|---|---|---|
| 1 | Amikacin | Amikin | Gram-negative infections (E. coli, Klebsiella, Pseudomonas aeruginosa); aerobic bacteria; tularemia | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA, preventing protein synthesis | Aminoglycosides | Aminoglycosides |
| 2 | Gentamicin | Garamycin | Gram-negative infections (E. coli, Klebsiella, Pseudomonas aeruginosa); aerobic bacteria; tularemia | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA, preventing protein synthesis | Aminoglycosides | Aminoglycosides |
| 3 | Kanamycin | Kantrex | Gram-negative infections; aerobic bacteria; tularemia | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA | Aminoglycosides | Aminoglycosides |
| 4 | Neomycin | Neo-Fradin | Gram-negative infections; topical infections; bowel preparation | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA | Aminoglycosides | Aminoglycosides |
| 5 | Netilmicin | Netromycin | Gram-negative infections; aerobic bacteria | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA | Aminoglycosides | Aminoglycosides |
| 6 | Tobramycin | Nebcin | Gram-negative infections; Pseudomonas aeruginosa; cystic fibrosis lung infections | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA | Aminoglycosides | Aminoglycosides |
| 7 | Paromomycin | Humatin | Intestinal parasitic infections; amoebiasis; leishmaniasis | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA | Aminoglycosides | Aminoglycosides |
| 8 | Streptomycin | - | Tuberculosis; tularemia; plague | Hearing loss; Vertigo; Kidney damage; Neurotoxicity | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA | Aminoglycosides | Aminoglycosides |
| 9 | Spectinomycin (Bs) | Trobicin | Gonorrhea | Hearing loss; Vertigo; Kidney damage | Binds to the bacterial 30S ribosomal subunit, inhibiting translocation of peptidyl-tRNA and causing misreading of mRNA | Aminoglycosides | Aminoglycosides |
| 10 | Geldanamycin | - | Experimental; antitumor antibiotic | Hepatotoxicity; GI upset | Binds the ATP-binding pocket of Hsp90 (heat shock protein 90), inhibiting its chaperone ATPase activity and causing client protein degradation via the ubiquitin-proteasome pathway (not an antibacterial mechanism; unrelated to the rifamycin RNA polymerase mechanism) | Ansamycins | Ansamycins |
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